방학동영어Kennedy-associated papers from the years 1955–1963, including X-rays and prescription records from the files of White House physician Dr. Janet Travell. According to Travell's records, during his presidential years Kennedy suffered from high fevers; stomach, colon, and prostate issues; abscesses; high cholesterol; and adrenal problems. Travell kept a "Medicine Administration Record," cataloguing Kennedy's medications: "injected and ingested corticosteroids for his adrenal insufficiency; procaine shots and ultrasound treatments and hot packs for his back; Lomotil, Metamucil, paregoric, phenobarbital, testosterone, and trasentine to control his diarrhea, abdominal discomfort, and weight loss; penicillin and other antibiotics for his urinary-tract infections and an abscess; and Tuinal to help him sleep."[19] Years after Kennedy's death, it was revealed that in September 1947, while Kennedy was 30 and in his first term in Congress, he was diagnosed by Sir Daniel Davis at The London Clinic with Addison's disease, a rare endocrine disorder. Davis estimated that Kennedy would not live for another year, while Kennedy himself hoped he could live for an additional ten.[368] In 1966, Dr. Travell revealed that Kennedy also had hypothyroidism. The presence of two endocrine diseases raises the possibility that Kennedy had autoimmune polyendocrine syndrome type 2 (APS 2).[369] Kennedy also suffered from chronic and severe back pain, for which he had surgery and was written up in the American Medical Association's Archives of Surgery. Kennedy's condition may have had diplomatic repercussions, as he appears to have been taking a combination of drugs to treat severe back pain during the 1961 Vienna Summit with Soviet Premier Nikita Khrushchev. The combination included hormones, animal organ cells, steroids, vitamins, enzymes, and amphetamines, and possible potential side effects included hyperactivity, hypertension, impaired judgment, nervousness, and mood swings.[370] Kennedy at one time was regularly seen by no fewer than three doctors, one of whom, Max Jacobson, was unknown to the other two, as his mode of treatment was controversial[371] and used for the most severe bouts of back pain.[372] Into late 1961, disagreements existed among Kennedy's doctors concerning his proper balance of medication and exercise. The president preferred the former, because he was short on time and desired immediate relief.[255] During that time, the president's physician, George Burkley, did set up some gym equipment in the White House basement, where Kennedy did stretching exercises for his back three times a week.[373] Details of these and other medical problems were not publicly disclosed during Kennedy's lifetime.[374] The President's primary White House physician, George Burkley, realized that treatments by Jacobson and Travell, including the excessive use of steroids and amphetamines, were medically inappropriate, and took effective action to remove the president from their care.[375] Dr. Nassir Ghaemi, a physician who reviewed Kennedy's medical records in his presidential archives, has opined that Kennedy's leadership (e.g. the 1962 Cuban Missile crisis and other events during 1963) improved greatly once the treatments of Jacobson had been discontinued and been replaced by a medically appropriate regimen under Burkley. Ghaemi concluded there was a "correlation; it is not causation; but it may not be coincidence either".[375] Personal tragedies Main article: Kennedy curse Kennedy and his family have experienced a number of personal tragedies. His older brother Joseph P. Kennedy Jr. was killed in action in 1944 at age 29, when his plane exploded over the English Channel during a first attack execution of Operation Aphrodite during World War II.[376] Kennedy's younger sister Rose Marie "Rosemary" Kennedy was born in 1918 with intellectual disabilities and underwent a prefrontal lobotomy at age 23, leaving her incapacitated for the rest of her life, until her death in 2005. His younger sister Kathleen Agnes "Kick" Kennedy died in a plane crash en route to France in 1948.